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Surface plasmon resonance gold

Surface plasmon resonance in gold nanoparticles: a revie

Surface plasmon resonances in strongly coupled gold

Surface Plasmon Resonance in Gold Ultrathin Nanorods and Nanowires | Journal of the American Chemical Society We synthesized and measured optical extinction spectra of Au ultrathin (diameter: ∼1.6 nm) nanowires (UNWs) and nanorods (UNRs) with controlled lengths in the range 20-400 nm Here, Au NPs with a mean diameter of around 35 nm show localized surface plasmon resonance (LSPR) at around 525 nm, which is in a good agreement with results reported in the literature.... Plasma.. Also application of surface plasmon resonance (SPR) of gold nanoparticles in the range of 500-600 nm is recently under investigation in photothermal inactivation of bacteria. Zharovet al. (2006) studied photothermal treatment of infections caused by a variety of bacteria using high-power pulsed Nd:Yag lasers . Despite their good results, some disadvantages were reported due to dangers of the high-power laser beams. In fact, high-power laser beams potentially causes more local. Surface plasmon resonance (SPR) was observed when a planar close-packed assembly of gold nanoparticles (Au NPs) is adsorbed at the water|1,2-dichloroethane interface. Aqueous gold nanoparticles , 13 or 16 nm in diameter, are deposited at the interface by adding methanol to form a close-packed film with a visible gold mirror reflectance Surface plasmon resonance (SPR) is the resonant oscillation of conduction electrons at the interface between negative and positive permittivity material stimulated by incident light. SPR is the basis of many standard tools for measuring adsorption of material onto planar metal (typically gold or silver) surfaces or onto the surface of metal nanoparticles

Surface plasmon resonance of gold nanoparticles as a

  1. Surface plasmon resonance in gold ultrathin nanorods and nanowires. Takahata R(1), Yamazoe S, Koyasu K, Tsukuda T. Author information: (1)Department of Chemistry, School of Science, The University of Tokyo , 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan
  2. In this study, we investigated use of local surface plasmon resonance (LSPR) of metal nanoparticles (NPs) as a correlative light and electron microscopy (CLEM) tag for biological samples. Gold NPs in ultra-thin sections for TEM revealed that LSPR could be observed by optical microscopy at sizes of 20 nm or larger. Gold NPs at sizes less than 20 nm could be observed using the gold enhancement method. Therefore, this CLEM tag could be applied to immunoelectron microscopy using this gold.
  3. The surface plasmon resonance wavelength in a gold film above silver nanospheres on a silica substrate was measured using transmission absorption spectroscopy
  4. Biosensors based on surface plasmon resonance (SPR) have shown significant applications in drug screening, environmental monitoring, immunoassay, etc.; however, improving the sensitivity of these biosensors is one of the prime tasks at present. In this study, taking advantage of the special optical and morp
  5. HYPOTHESIS: We hypothesize that surface plasmon resonance imaging (SPRi) of interactions between small organic compounds and gold is influenced by the refractive index and chemical structures of the compounds. EXPERIMENTS: For the first time we imaged the SPR signals upon interaction of a gold surface with seven compounds representing aromatic, cyclic, short chain, and long chain carbon structures using an array format. FINDINGS: The refractive index and chemical structures of the tested.
  6. Die Oberflächenplasmonenresonanzspektroskopie (englisch surface plasmon resonance spectroscopy, SPR-Spektroskopie) ist ein spektroskopisches Analyseverfahren, welches der schnellen und unkomplizierten quantitativen Bestimmung von Schichtdicken im Nanometerbereich dient

In the last two decades, plasmon resonance in gold nanoparticles (Au NPs) has been the subject of intense research efforts. Plasmon physics is intriguing and its precise modelling proved to be challenging. In fact, plasmons are highly responsive to a multitude of factors, either intrinsic to the Au NPs or from the environment, and recently the need emerged for the correction of standard electromagnetic approaches with quantum effects. Applications related to plasmon absorption and. Coupling surface plasmon resonance of gold nanoparticles with slow-photon-effect of TiO 2 photonic crystals for synergistically enhanced photoelectrochemical water splitting X. Zhang, Y. Liu, S. Lee, S. Yang and Z. Kang, Energy Environ A crucial aspect for these applications is how the surface plasmon resonance of metal nanoparticles is modified after assembly with graphene. Here, we used the discrete dipole approximation method to study the surface plasmon resonance of silver and gold nanoparticles in the proximity of a graphene flake or embedded in graphene structures

Barrow S., Funston A., Gomez D., Davis T., Mulvaney P. Surface plasmon resonances in strongly couple gold nanoparticle chains from monormer to hexamer. Nano Lett. 11, 4180-4187 (2011) The impact of different gold nanoparticle (GNP) structures on plasmonic enhancement for DNA detection is investigated on a few-layer graphene (FLG) surface plasmon resonance (SPR) sensor. Two distinct structures of gold nano-urchins (GNu) and gold nanorods (GNr) were used to bind the uniquely designed single-stranded probe DNA (ssDNA) of Mycobacterium tuberculosis complex DNA. The two types of GNP-ssDNA mixture were adsorbed onto the FLG-coated SPR sensor through the π-π stacking force. In summary, surface plasmon resonances sensor based on the gold cube array is investigated using FDTD simulations. The sensor consists of a two-dimensional array of gold cubes placed on quartz pillar on quartz substrate. Transmission spectra of such structure are calculated, and the effects of the structure parameters lattice perio The temperature dependences of energy and width of the surface plasmon resonance were studied for gold nanoparticles with sizes 20-55 nm in silica host matrix in the temperature range 17-915 °С. The increase of temperature leads to appreciable red shift and broadening of the surface plasmon resonance in Au nanoparticles. The obtained dependences were analyzed within the framework of theoretical model considering the thermal expansion of the nanoparticle, the electron. The gold layer is many wavelengths thick, with a refractive index of n m = 0.238+3.385i at a wavelength of 632.8nm. A 1D FDE solver region is used. Analysis. The analytical solutions for the effective index and propagation loss for the surface plasmon modes are given by the following expressions: $$ N_{s p}=\frac{k_{s p}}{k_{o}} $

Gold Nanoparticles - Surface Plasmon Resonance

The surface plasmon resonance frequencies of gold nanoparticles and films embedded in various semiconductor matrices were found to be in the spectral range of 500-700 nm [54] [55][56][57][58][59. Layer-by-layer gold nanoparticles are used to generate photocurrent in an environmentally-friendly plasmon-sensitized solar cell towing to surface plasmon resonance. The efficiency of the.

Surface plasmon resonance based highly sensitive gold

Surface plasmon resonance imaging of gold-small molecule interactions is influenced by refractive index and chemical structures. Al Mubarak ZH(1), Ramesh R(2), Liu L(3), Krishnan S(4). Author information: (1)Department of Chemistry, Oklahoma State University, Stillwater, OK 74078, United States Surface Plasmon Resonance Plasmonics. SPR (surface plasmon resonance) is a physical process that is observed when polarized light hits a metal... The Prism with the thin Gold layer. Finding a prism on which a metal film is deposited is a problem. A valid alternative... Experimental Setup. The. Surface Plasmon Resonance Localized surface plasmon resonance is generated by metal nanoparticles, typically gold and silver. LSPR produces a strong resonance peak in the visible range of light, with its position being highly sensitive to the local refractive index surrounding the particle. Using localized surface plasmon resonance simplifies. Gold Nanoparticle-Functionalized Surface Plasmon Resonance Optical Fiber Biosensor: In Situ Detection of Thrombin With 1 n·M Detection Limit Abstract: We present an optical fiber biosensor that employs both long-range and localized surface plasmon resonances (SPRs) to sensitively detect very small changes in the resonances due to the surrounding refractive index. A tilted optical fiber Bragg.

Surface plasmon resonance for the characterization of

Tuning the Surface Plasmon Resonance of Gold Dumbbell

Surface Plasmon Resonance in Gold Ultrathin Nanorods and

  1. Surface plasmon resonance (SPR) has become an important optical biosensing technology in the areas of biochemistry, biology, and medical sciences because of its real-time, label-free, and noninvasive nature. The high cost of commercial devices and consumables has prevented SPR from being introduced in the undergraduate laboratory. Here we present an affordable homemade SPR device with all of.
  2. One at ∼ 490 nm, resulting from the resonant absorption of gold films, is independent of nanopore sizes and dielectric surroundings. The other at ∼ 550 - 650 nm, arising from the excitation of localized surface plasmon resonance, shows obvious band shift with the nanopore sizes and dielectric indices of surrounding media, suggesting that NPG is a promising candidate as plasmonic sensors.
  3. Gold -nanoshells as surface plasmon resonance (SPR) K. Sathiyamoorthy and Michael C. Kolios* Ryerson University, Department of Physics, 350 Victoria Street, Toronto, Ontario, M5B 2K3 Canada *mkolios@ryerson.ca ABSTRACT Coreshell plasmonic nanoparticles (CS) are a class of nanoparticles that exhibit optical absorption in the near IR regime and have potential biomedical applications in imaging.
  4. SURFACE PLASMON RESONANCE SENSORS Akil Mannan Matcheswala University of Kentucky, matcheswala@gmail.com Right click to open a feedback form in a new tab to let us know how this document benefits you. Recommended Citation Matcheswala, Akil Mannan, GOLD NANOSPHERES AND GOLD NANORODS AS LOCALIZED SURFACE PLASMON RESONANCE SENSORS (2010). University of Kentucky Master's Theses. 60. https.
  5. We demonstrate that coupling between grating diffraction and localized surface plasmons in two-dimensional gold nanoparticle arrays in water leads to narrow near-infrared resonance peaks in measured far field extinction spectra. Good agreement is obtained between finite difference time domain (FDTD) calculations and experimental extinction spectra

(PDF) Surface Plasmon Resonance in Gold Nanoparticle

  1. Effects of size, morphology, and composition of gold and silver nanoparticles on surface plasmon resonance (SPR) and surface enhanced Raman spectroscopy (SERS) are studied with the purpose of optimizing SERS substrates. Various gold and silver films made by evaporation and subsequent annealing give different morphologies and compositions of nanoparticles and thus different position of the SPR.
  2. In this paper, we numerically demonstrate a two-layer circular lattice photonic crystal fiber (PCF) biosensor based on the principle of surface plasmon resonance (SPR). The finite element method (FEM) with circular perfectly matched layer (PML) boundary condition is applied to evaluate the performance of the proposed sensor. A thin gold layer is deposited outside the PCF structure, which acts.
  3. Surface plasmon resonance (SPR) extinction spectra of single gold nanodisk has been studied by FDTD method. The calculation results reveal that extinction spectra shift can be controlled by tuning radius and height of the particle, which presents a potential application for design and fabrication of optical devices based on SPR. We also obtain the structure parameters of a gold nanodisk whose.
  4. The surface plasmon damping induced by high excitation of the electron gas is studied in femtosecond pump-and-probe experiments on gold colloids embedded in a sol-gel matrix. Optical excitation of single-particle interband transitions leads to a pronounced broadening of the surface plasmon line. A similar behavior is observed for resonant excitation of the surface plasmon

Both surface plasmon resonance (SPR) spectroscopy and its counterpart, localized surface plasmon resonance (LSPR) spectroscopy, have been accepted as important means for carrying out not only nanostructure characterization but also label-free chemical and biological sensing. SPR spectroscopy is mostly used in biosensing, especially when investigating binding affinities, such as antibody. Our company provides optimal solutions Surface Plasmon Resonance (SPR) technique since 1998. We offer measurement equipment for small laboratories and universities. Our SPR devices allow to run experiments in liquid or air environments as well as electrochemical in situ measurements. Our company offers the wide range of a high quality Au coated glass plates for SPR or another biochemical.

Localized surface plasmon resonance is generated by metal nanoparticles, typically gold and silver, as compared to a continuous film of gold as used in traditional SPR. OpenSPR is similar in many ways to traditional SPR, and provides the same data using the same experimental conditions and procedures. To the user, everything would seem the same [ Self - assembly Gold Nanoislands for Localized Surface Plasmon Resonance Biosensing C hi - Man Lawrence Wu and S iu - P ang Ng Department o f Physics and Materials Science , City University of Hong Kong, Hong Kong SAR, P. R. China ABSTRACT Localized surface plasmon resonanc e (LSPR) is a label - free biosensing technique employing plasmonic nanostructures to detect local refractive index. In this report, we demonstrate the use of functionalized gold nanorods as amplification labels for ultra-sensitive surface plasmon resonance biosensing. Drastic sensitivity enhancement, owed to the electromagnetic interaction between the nanotag and the sensing film, was maximized using longitudinal plasmonic resonance of gold nanorods. The detection sensitivity of the nanorod-conjugated. Hello, we provide concise yet detailed articles on Gold Choices: Surface Plasmon Resonance Of Gold Nanoparticles topic. The information here is sourced well and enriched with great visual photo and video illustrations. When you find the article helpful, feel free to share it with your friends or colleagues Surface Plasmon Resonance with Electrospun Nanofibers on Gold Surface Kazuma Tsuboi1, Hidetoshi Matsumoto1, Mie Mnagawa1, and Akihiko Tanioka1 1Department of Organic and Polymeric Materials, Tokyo Institute of Technology, 2-12-1 Ookayama, Meguro-ku, Tokyo, 152-8552, Japan. . ABSTRACT In this paper we report new excitation method of surface plasmon polariton (SPP) a

Surface plasmon resonance of naked gold nanoparticles for

  1. Surface Plasmon Resonance Enhanced Magneto-Optics (SuPREMO): Faraday Rotation Enhancement in Gold-Coated Iron Oxide Nanocrystals Prashant K. Jain,† Yanhong Xiao,‡ Ronald Walsworth,‡,§ and Adam E. Cohen*,†,§ Department of Chemistry and Chemical Biology, Department of Physics, HarVard UniVersity, Cambridge, Massachusetts, 02138, and HarVard-Smithsonian Center fo
  2. Surface plasmon resonance (SPR) is an optical phenomenon that occurs on the metal (normally gold or silver) film surface and the light that excited this phenomenon changes with the refractive index of materials on the metal surface. SPR sensors are constructed based on this phenomenon and are used in fields of biological and chemical analyses, drug screening, environmental monitoring, and so on
  3. Surface plasmon resonance (SPR) spectroscopy, as well as its counterpart, localized surface plasmon resonance (LSPR) spectroscopy, has been recognized as an invaluable tool for label fee chemical and biological sensing; as well as nanostructure characterization. The most common application of SPR spectroscopy is in the field of biosensing, particularly the study of binding affinities, such as.
  4. g Wang, and Ji
  5. e, gold thin film INTRODUCTION Since the first report on the phenomenon of surface plasmon resonance (SPR) (studies on processes taking place on metal surfaces and the detection of gases)
  6. ation of kinetics, affinity, or analyte concentration)

Surface plasmon resonance of gold nanoparticles assemblies

Localized Surface Plasmon Resonances: Noble Metal

Plasmetrix Surface Plasmon Resonance device: Compact Optical Research Instruments ``CORgI``. Low cost SPR Liquid delivery system. SPR user friendly software. Surface Plasmon Resonance portable device with large sensing spot and open measurement cell (petri dish for live cells detection) Surface-plasmon-resonance (SPR) is a quantum-electromagnetic phenomenon arising from the interaction of light with free electrons at a metal-dielectric interface. At a specific angle/wavelength of light, the photon's energy is transferred to excite the oscillation of the free electrons on the surface. A change in the refractive-index (RI) may occur, which is influenced by the analyte.

Surface plasmon resonance - Wikipedi

The surface plasmon resonance technique allows direct, real-time kinetic measure- ments of the interaction of unlabelled biological molecules at surfaces. After a brief discussion of the principles of surface plasmon resonance, we review its application to the nonspecific adsorption of protein, the formation of phospholipid bilayers, membrane-protein interactions and DNA hybridization. The. Surface plasmon resonance refers to the electromagnetic response that occurs when plasmons are oscillating with the same frequency on the surface of a material. As these plasmons oscillate at specific resonant frequencies, they move with periodic driving forces that can become large amplitude oscillations when they interact. This phenomenon is stimulated by a light source. The frequency of the. Colorimetric detection based on localised surface plasmon resonance of gold nanoparticles: Merits, inherent shortcomings and future prospects [2016 Hence, the main potential of surface plasmon resonance is characterization of medium after the metal layer. Sometimes polymer layer was coated on gold later for detection and improvement the sensor performence. So, the properties of nanostructures gave rised to interest in biosensing. Nano particles andNano tube have improved the sensitivity.

Surface plasmon resonance in gold ultrathin nanorods and

  1. We will locate the Surface Plasmon Resonance of a 50 nm silver film on glass at 500nm by analyzing the reflection and transmission as a function of the source angle of incidence. Angles with low reflection and transmission (high absorption) indicate that power from the source is exciting (coupling into) the SPR mode. We also calculate the dispersion relation of the SPR modes. Finding the SPR.
  2. Surface Plasmon Resonance. BioRad Proteon XPR36. ProteOn User Manual. The Proteon XPR36 exploits the optical phenomenon of surface plasmon resonance (SPR) to provide real time monitoring of interactions between molecules. A molecule (the ligand) is immobilized on a gold surface using any of a variety of available chemistries. The interaction of light with the gold surface generates a surface.
  3. g that the wavelength of visible light incident on the conductive layer through the transparent medium layer is λ (nm), the periodicity of the periodic structure is (λ/633)×100 nm to (λ/633)×500 nm.

Surface plasmon resonance technique in collaboration with optical fiber technology has brought tremendous advancements in sensing of various physical, chemical, and biochemical parameters. In this review article, we present the principle of SPR technique for sensing and various designs of the fiber optic SPR probe reported for the enhancement of the sensitivity of the sensor Surface plasmon resonance In order to describe SPR, it is helpful to start with the phenomenon of total internal reflection (TIR) which occurs at an interface between non-absorbing media. When a light beam propagating in a medium of higher refractive index meets an interface at a medium of lower refractive index at an angle of incidence above a critical angle (see Mirabella [8], de Mello [9. Surface Plasmon Resonance (SPR)-based optical biosensors offer an increasingly effective technology to detect molecular interactions in real time [1,2]. In the last decade, the use of biosensors is enormously increased [3], for molecular recognition in an increasing number of different research fields [4-9]: a fundamental advantage is that biomolecular interactions, ranging from the millimolar. The resonance phenomena of surface plasmons has enabled development of a novel class of noncontact, real-time and label-free optical sensors, which have emerged as a prominent tool in biochemical sensing and detection. However, various forms of surface plasmon resonances occur with natively strong non-radiative Drude damping that weakens the resonance and limits the sensing performance.

Local surface plasmon resonance of gold nanoparticles as a

Surface plasmon resonances in periodic and random patterns of gold nano-disks for broadband light harvesting Yoshiaki Nishijima,1,∗ Lorenzo Rosa,2 and Saulius Juodkazis2,3 1Department of Electrical and Computer Engineering, Graduate School of Engineering, Yokohama National University, 79-5 Tokiwadai, Hodogaya-ku, Yokohama 240-8501, Japa Surface plasmon resonances of protein-conjugated gold nanoparticles on graphitic substrates Anh D. Phan,1,2,a) Trinh X. Hoang,2 Thi H. L. Nghiem,2 and Lilia M. Woods1 1Department of Physics, University of South Florida, Tampa, Florida 33620, USA 2Institute of Physics, 10 Daotan, Badinh, Hanoi, Vietnam (Received 28 May 2013; accepted 8 October 2013; published online 17 October 2013

Surface plasmon-related resonances on deep and asymmetric gold gratings M. Kreiter, S. Mittler, and W. Knoll Max Planck Institut fu¨r Polymerforschung, Ackermannweg 10, D-55128 Mainz, Germany J. R. Sambles Department of Physics, University of Exeter, Exeter, Devon EX4 4QL, England ~Received 3 May 2001; published 13 March 2002! Based on theoretical calculations, the surface plasmonlike. Localized surface plasmon resonance (LSPR) peak wavelength of nanostructures metallic materials, such as gold and silver, is very sensitive to the dielectric environment of the materials; hence widely used as sensors to detect various types of chemicals. In this study, high - yield gold nanoplates ca. 63% have been grown on the quartz substrate using the seed - mediated growth method For Au-based surface Plasmon resonance sensor up to two times increased sensitivity can be achieved using dielectric coating with high refraction index 2.3 of proper thickness. For sensors based on aluminum we were able to achieve 50% increased angular sensitivity. At the same time width of the reflectivity dip increased proportionally to the optical thickness of the dielectric coating. For.

parameters of nanoparticles affecting surface Plasmon resonance wavelength of gold and silver nanoparticles. The available data lead us to two different equations, one for silver and one for gold nanoparticles which correlate their size, concentration and wave-length. For gold nanoparticles, the equation came out to be 0.012log 0.36 196 10 324 cg x sgg − = ×+ ×+ Where conc. is inppb(×1018. Gold Nanoparticles Localized Surface Plasmon Resonance ABSTRACT How to cite this article Davatgaran Taghipour Y, Kharrazi S, Amini SM. Antibody Conjugated Gold Nanoparticles for Detection of Small Amounts of Antigen Based on Surface Plasmon Resonance (SPR) Spectra. Nanomed Res J, 2018; 3(2): 102-108. DOI: 10.22034/nmrj.2018.02.007 This work is licensed under the Creative Commons Attribution 4. PhotoacousticandPhotothermalPhenomena 363 400 600 800 Rods Spheres PA signal Wavelength (nm) Fig. 2. PAspectraofgoldnanoparticlesofdif-ferentshapes

Gold nanoparticles applicationsSensors | Free Full-Text | Photonic Crystal Fiber-Based

All the gold nanofluids showed better photothermal conversion characteristics than H 2 O due to the strong localized surface plasmon resonance (LSPR) effect. The increase in gold nanoparticles diameters resulted in lower photothermal conversion properties, so the appropriate reducing agents have great influence on the optical properties of gold nanofluids in our experimental system. Trisodium. Surface Plasmon Polaritons (SPPs) -Introduction and basic properties Standard textbook: - Heinz Raether, Surface Plasmons on Smooth and Rough Surfaces and on Gratings Springer Tracts in Modern Physics, Vol. 111, Springer Berlin 1988 Overview articles on Plasmonics: - A. Zayats, I. Smolyaninov, Journal of Optics A: Pure and Applied Optics 5, S16 (2003) - A. Zayats, et. al., Physics Reports 408. The near infrared (NIR) fluorescence enhancement by local surface plasmon resonanoce from arrayed gold (Au) nanoblocks was investigated by NIR fluorescent dyes, IR780, immobilized in hydrophobic DNA thin film on glass sub- strates, to clarify the gap mode effect on the fluorescence enhancement. In the substrate with Dimer type Au nanoblock arrangement, average total fluorescence intensity was. This paper reports, for the first time, a gold-silver alloy film based broadband spectral surface plasmon resonance imaging (SPRI) sensor that enables in situ quantitative detection of chemical and biological molecules adsorbed on the partial or entire surface of the alloy film. The use of the gold-silver alloy film as the sensing layer makes the SPRI sensor lower in detection cost and higher.

Biosensors | Free Full-Text | One-Pot Synthesis of MultiFrom tunable core-shell nanoparticles to plasmonicPPT - GOLD NANOPARTICLE PATTERNING BY SELF-ASSEMBLY ANDGold nanorod-covered kanamycin-loaded hollow SiO 2 (HSKAuUnconjugated Gold Colloids or Sols

Herein, DA DNA aptamer (DAAPT) gold nanoparticle (AuNP) conjugate is utilized to enhance the surface plasmon resonance (SPR) signal, which enables to detect and quantify DA in the femtomolar (200 fM) to picomolar range. To the best of our knowledge, this is the lowest detection limit achieved for SPR sensing of dopamine. The as-prepared 10 nm DAAPT-AuNP conjugate demonstrates strong binding. In this paper, a gold nano-urchins enhanced plasmonic sensor is demonstrated for the detection of a typical breast cancer marker, estrogen receptor alpha (ER). The localized field confinement effect due to the sharp features of the nano-urchins amplifies the biosensing signal and improves its sensitivity as compared to a conventional surface plasmon resonance (SPR) biosensor CONFERENCE PROCEEDINGS Papers Presentations Journals. Advanced Photonics Journal of Applied Remote Sensin APPLIED PHYSICS LETTERS 92, 103105 共2008兲 Synthesis of gold-silicon core-shell nanoparticles with tunable localized surface plasmon resonance S. Mohapatra,1,a兲 Y. K. Mishra,1 D. K. Avasthi,1 D. Kabiraj,1 J. Ghatak,2 and S. Varma2 1 Inter-University Accelerator Centre, Post Box 10502, New Delhi 110067, India 2 Institute of Physics, Sachivalaya Marg, Bhubaneswar 751005, India 共Received. ETH Localized surface plasmon resonance (LSPR) is a promising method for detecting antigen-antibody binding in label-free biosensors. In this study, the fabrication of a LSPR substrate with a gold nanodot array through the lift-off process of an alumina mask is reported. The substrate showed an extinction peak in its extinction spectrum, and the peak position was dependent on the height of the.

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